NAPLEX Terms & Definitions Practice Test

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Aminoglycoside MOA
Selegiline Anipryl, Eldepryl, Emsam, Zelapar, Rasagiline Azilect
Inhibits bacterial protein synthesis by binding to 30S ribosomal subunit
Atypical coverage, gram coverage and some gram -, QT prolongation esp erythro and clarithro, alternative for PCN allergy, hepatically cleared, Azithromycin renally dosed when CrCl 10 ml/min
Cover gram negative bugs, concentration dependent killing, post antibiotic effect, nephrotoxic, ototoxic, neurotoxic, pregnancy category D, dose on IBW or Adjusted BW, renally dosed