| Bind to 50S ribosomal subunit to inhibit protein synthesis | |
| Carbamazepine, phenobarbital, phenytoin, rifampin | |
| Pravastatin, low dose atorvastatin, or low dose rosuvastatin-except with indinavir or saquinavir | |
| Cimetidine, esomeprazole, etravirine, efavirenz, fluoxetine, fluvoxamine, isoniazid, ketoconazole, modafinil, omeprazole, topiramate, voriconazole |