| Penicillin G Gentamicin or Streptomycin | |
| Isoniazid, Rifampin, Pyrazinamide, Ethambutol | |
| Between 5 and 10 percent | |
| Atypical coverage, covers spirochetes, anthrax, syphillis and urinary VRE, tooth discoloration, fixed drug eruption, pregnancy category D, mineral cations inhibit absorption, increase INR, anticonvulsants decrease tetracycline levels |