| Bind to 50S ribosomal subunit to inhibit protein synthesis | |
| Oxazolidinone, binds to 23S to inhibit protein synthesis, gram MRSA all VRE, headache, Myelosuppression 14 day, diarrhea, increased pancreatic enzymes, weak MAOI, no renal dosing | |
| Amiodarone, clarithromycin, cyclosporine, erythromycin, itraconazole, propafenone, spironolactone, quinidine, verapamil | |
| Peak 20-30 and trough 5 |