| 50 percent | |
| Cimetidine, esomeprazole, etravirine, efavirenz, fluoxetine, fluvoxamine, isoniazid, ketoconazole, modafinil, omeprazole, topiramate, voriconazole | |
| TCAs, SSRIs citalopram, SNRIs, trazadone | |
| Pravastatin, low dose atorvastatin, or low dose rosuvastatin-except with indinavir or saquinavir |